The latest and most mainstream technologies and the most promising investment projects are all here.
On May 23rd, 2024, the 9th Bio-based Conference and Exhibition (referred to as Bio-ba)Sed 2024) was grandly opened in Shanghai. More than 1,500 people from various government parks, academicians and experts from bio-based industries at home and abroad, top scholars, industry associations and representatives from upstream and downstream industries attended the meeting.
The conference was hosted by Zhejiang Key Laboratory of Bio-based Polymer Materials Technology and Application, Ningbo Detai Zhongyan Information Technology Co., Ltd. (DT New Materials), and co-organized by Bio-based Materials Professional Committee of China Bioengineering Society, Biotechnology and Materials Special Committee of China Composite Materials Industry Association, Shanghai Synthetic Bio-industry Association and Hangzhou Yunshang New Materials Co., Ltd.
The forum on exchange of scientific and technological achievements will be held on May 23-24, including a special session of "exchange of scientific and technological achievements", "new technology conference" and "investment", with a total of 20+ special reports, showing practical technology models, effectively controlling the core of the survival and growth of bio-based industries, and bringing more clear and broader market increments to bio-based enterprises and scientific research units.
01, scientific and technological achievements exchange special session on the afternoon of May 23rd.
Moderator: Andy Lau, Professor Tsinghua University, Director of Institute of Applied Chemistry, Department of Chemical Engineering, Tsinghua University.
Professor Hu Wei from Northeast Normal University shared a special report on the theme of "Development and Utilization of Lignin-based Bio-based Chemicals". In this report, through the design of hydrophilic functional molecular structure of lignin, we broke through the international blank of key technology for preparing environmentally-friendly water-soluble lignin-based carbon fiber (CF) sizing agent, and developed a flame-retardant CF reinforced composite with excellent comprehensive properties.
Shen Chunjuan, R&D Manager of Asia-Pacific Region of Novartis Separation Technology (Shanghai) Co., Ltd., shared a special report on the theme of "How high-efficiency separation and purification technology can further reduce carbon emissions in the production of bio-based products". The report introduces that Novartis will optimize its purification process for bio-based products, reduce the consumption of chemicals and energy, improve the product yield and reduce the total amount of waste discharge, which will play a vital role in the overall carbon emission control in the production of bio-based products.
Professor Chen Guoqiang from Tsinghua University shared a special report on the theme of "Production and application of polyhydroxyalkanoate PHA". In this report, halophilic bacteria were transformed from scratch, so that they can efficiently produce various chemicals and materials by using seawater as the medium without sterilization and continuous process. The halophilic bacteria achieved ultra-high PHA accumulation (92%) and controllable deformation through the transformation of synthetic biology, and obtained a variety of PHA, small molecular chemicals and enzyme products.
Professor Zhu Xiaoxia of Beijing Normal University shared a special report on the theme of "Green Chemistry Method for Polymer Synthesis and Transformation". In this study, immobilized lipolytic enzyme was used to prepare macrocyclic monomers containing ester bonds, and then the same enzyme catalyst was used for entropy-driven ring-opening polymerization to prepare degradable polyester materials. In addition, the team successfully used glucose oxidase as catalyst to modify the polymers with short-arm sugar side groups of polyethylene glycol, and prepared carboxyl-containing copolymers.
Chairman Chu Junzheng of Henan Zhengtong Food Technology Co., Ltd. shared a special report on the theme of "Structural and functional characteristics and application development of bio-based isosorbide". The report introduces the structural characteristics and industrialization demonstration of isosorbide, and discusses the application research of IS in the fields of polymer materials with commercial value such as polycarbonate, polyester, polyurethane and bio-based plasticizer.
Chairman Yang Jizhi of Shanghai Anci Environmental Protection Technology Co., Ltd. shared a special report on the theme of "Introduction to the filtration and purification technology of the new generation of biological fermentation broth", which introduced the membrane technology purification process of Anhorn fermentation broth and the extraction and purification process of the effective components of Anhorn fermentation broth.
On the afternoon of 23rd, the round-table dialogue session was hosted by Professor Meng Yuezhong of Sun Yat-sen University, and discussed with Professor Chen Guoqiang of Tsinghua University, Professor Shao Ziqiang of Beijing Institute of Technology, Chairman Chu Junzheng of Henan Zhengtong Food Technology Co., Ltd. and Professor Zhu Xiaoxia of Beijing Normal University "How to break the situation of bio-based chemicals in China as soon as possible and achieve overtaking in industrialized corners?" This discussion mainly focuses on the key technology evaluation of efficient co-production of bio-based chemicals from non-grain biomass, the advantages of bio-based chemicals synthesized by PK chemical method and its downstream application, and the development status and challenges of bio-based chemicals in China.
Moderator: Meng Yuezhong, Dean of the Institute of Carbon Neutralization Technology of Sun Yat-sen University and Chief Scientist of the Institute of Chemistry of Henan Academy of Sciences.
02, new technology release special on the afternoon of May 23rd.
Chen Jing, a researcher from Ningbo Institute of Materials Technology and Engineering, China Academy of Sciences, shared a special report on the theme of "Construction and Performance Control of Bio-based Polyurethane Foam". Aiming at the frequent marine leakage accidents, this report develops a series of efficient foam composite oil-absorbing materials with biomass source, and its degradation rate is three times that of commercially known degradable polyurethane foam materials. At the same time, the foam material was treated with in-situ antibacterial treatment to realize the application of bio-based polyurethane foam in biomedical field.
Wen Zhiqiang, CEO of Nanjing Gas Biochemistry Technology Co., Ltd., shared a special report on the theme of "Bio-butanol /CO, Technology Development of Bio-butanol". The report introduces that the development of synthetic biology has promoted the development of genetic operation tools and chassis debugging of Clostridium producing n-butanol, and greatly improved the efficiency of Clostridium using biomass/industrial tail gas and its ability to produce n-butanol. Synthetic biotechnology, combined with double carbon policy and industrial capital, is strongly driving the production capacity and commercialization of bio-based butanol and CO2-based butanol.
Professor Nie Yong from Zhejiang University of Technology shared a special report on the theme of "Study on the preparation technology of long-chain dibasic acid of bio-based polyester monomer-azelaic acid". The report puts forward a new process of preparing bio-based azelaic acid from biodiesel. Compared with the traditional process of preparing azelaic acid from oleic acid, it has the advantages of wide source of raw materials, easy separation and high product quality. The purity of azelaic acid after separation and purification can reach over 99.5%, and at the same time, it can produce high value-added products such as monomethyl azelaic acid, nonanoic acid and caproic acid.
03, scientific and technological achievements exchange special session on the morning of May 24th.
Moderator: Huang Yong, researcher, Institute of Physical and Chemical Technology, Chinese Academy of Sciences.
Professor Yu Haipeng from Northeast Forestry University shared a special report on the theme of "New Technology for Green Large-scale Preparation of Nano-cellulose". Starting from the preparation idea of nano-cellulose, the report introduces several green, low-cost and large-scale preparation methods of nano-cellulose and the outstanding characteristics of the products through research examples. It is hoped that the report sharing will promote the industrialization development of nano-cellulose.
Professor Li Zhibo from Qingdao University of Science and Technology shared a special report on "Chemical Synthesis and Properties of Biopolymer P4HB". In this report, the chemical synthesis of bioplastics P4HB was realized by developing efficient synergistic catalytic system and near-equilibrium polymerization method, and P4HB bioplastics with controllable molecular weight and terminal functional groups were obtained, and polyurethane with controllable depolymerization properties was developed based on P4HB prepolymer.
Professor Wang Zhongkai of Anhui Agricultural University shared a special report on the theme of "Chemical Transformation of Vegetable Oils and Preparation of Bio-based Nylon". The report focuses on the high-efficiency chemical transformation of vegetable oils and the synthesis of high-performance bio-based polymer materials, especially on the combination of production, learning and research, and develops vegetable oils to prepare high-performance bio-based nylon with high toughness, low temperature resistance and low water absorption.
Sun Hanyu, Deputy Secretary-General of Biotechnology and Materials Committee of China Composite Materials Industry Association, shared a special report on the theme of "How bio-based materials enterprises use the leader standard to build enterprise moat". The report made an interpretation of the national standardization development outline and the leader standard for everyone.
Researcher Apollo from Institute of Microbiology, China Academy of Sciences shared a special report on the theme of "Green Synthesis and Manufacture of Bio-based Chemicals". Through route design, rational transformation of catalytic components and optimization of cell performance system, the team has achieved a number of biotechnological substitutes for chemical raw materials and production processes. The report introduces the progress made by the research team in the design of biosynthetic routes for high-value chemicals and pharmaceutical chiral intermediates, optimization of cell factories and industrial development.
On the morning of 24th, the round-table dialogue session was hosted by Professor Yu Long of South China University of Technology, and discussed "the industrial chain construction of bio-based plastics from laboratory to shelf" together with researcher Huang Yong from Institute of Physical and Chemical Technology of Chinese Academy of Sciences, professor Li Zhibo from Qingdao University of Science and Technology, researcher Apollo from Institute of Microbiology of China Academy of Sciences, researcher Zhang Jun from Institute of Chemistry of Chinese Academy of Sciences and professor Zhou Ruowan from Southwest Jiaotong University. The round-table discussion mainly focuses on the key factors of how to quickly break away from the laboratory and connect with the industry in the production of bio-based materials with biocatalysis as the core, how to quickly expand the application scenarios of bio-based materials, improve the substitution rate of fossil raw materials products, and how to make bio-based products walk on the shelves from the laboratory.
Moderator: Yu Long, professor of South China University of Technology and chief scientist of Institute of Chemistry, Henan Academy of Sciences.
04. Investment cooperation special session on the afternoon of May 24th.
Moderator: chenchen, managing partner of Junyi Capital.
Commentators and participating employers:
Suzhou Industrial Park Yuansheng Venture Capital Management Co., Ltd., Yida Equity Investment Fund Management Co., Ltd., Shanghai Shengyu Equity Investment Fund Management Co., Ltd., China Energy Saving Science and Technology Innovation Investment Co., Ltd., Feitu Venture Capital (Beijing) Co., Ltd., Lejin Chemical (China) Investment Co., Ltd., Dasailu (China) Investment Co., Ltd., Luye Investment Group Co., Ltd., Volkswagen (China) Investment Co., Ltd., Beijing Woyan Capital Management Center (Limited) …
Roadshow Report: Preparation Technology and Industrialization of Polylactic Acid Homogeneous Microspheres
The preparation technology of homogeneous emulsion and microsphere microcapsules independently developed by this project solved these technical problems, and undertook three national key projects of new drug creation in the development of microsphere preparations. This technology won the second prize of national technological invention and the first prize of Beijing science and technology, and successfully achieved the transformation of results, making important contributions to social economy.
Roadshow Report: Application of New Bio-based PDI Formaldehyde-free Adhesive in Molded Packaging Materials and Development of PUR Hot Melt Adhesive Modification
In this project, a new type of bio-based polyurethane adhesive was successfully developed by using the abundant plant waste materials such as sawdust and straw in Linyi and Heze, Shandong Province, and relying on the bio-based aliphatic 1,5- pentadicyanate ester (PDI) produced by Yinguang, Gansu Province, and a new type of bio-based PDI logistics tray was produced by one-time high-efficiency industrial production mode.
Roadshow Report: Synthetic Biology Drives the Landing and Industrialization of Green/Negative Carbon Butanol Technology
This project adopts the leading domestic engineering anaerobic fermentation technology of Clostridium aeruginosum to transform industrial tail gas (mainly composed of CO/H2/CO2) or green hydrogen/green carbon to produce butanol and feed protein, which has obvious quality and cost advantages.
Roadshow report: biological long-chain dibasic acid and its application industrialization
This project can replace the independent intellectual property synthetic biological technology project of traditional production mode. Long-chain dibasic acid products are widely used in biomedicine, fine chemicals, new materials and other fields, and can realize domestic substitution, iterative upgrading and industrial chain construction. At present, it can realize 10,000 tons of industrialization and achieve the sales target of 10 billion yuan.
Roadshow Report: Bio-intelligence Empowering Spider Silk Protein Production and Commercial Application
Through AI-assisted protein design, expression system transformation, chassis cell design and fermentation process optimization, this project has successfully achieved efficient production of spider silk protein in a ton tank, and designed and produced "Lingsi" protein regenerated fiber through wet spinning process.